I use GPT slices over the disks, because that gives ability to make
portable labels, which can be accessed through /dev/gpt/LABEL paths.
=> https://en.wikipedia.org/wiki/GUID_Partition_Table

=> ZFS is everywhere

I trust only cryptographic hashes for integrity checksums.
Currently I use Skein in ZFS, because it is much faster than
SHA2-512/2 (and SHA2-256 of course).
=> Skein

Transparent compression is enabled on all datasets. I see no bottleneck
or any noticeable CPU burning with Zstandard} algorithm, comparing to
previously used LZ4.
=> Zstandard
=> LZ4

Several disks are still encrypted with native FreeBSD's GELI AES-XTS
FDE. But I tend to use native ZFS encryption now, just because of
convenience and flexibility. However I would like to see
ChaCha20-Poly1305 algorithm there, instead of AES-GCM.
=> GELI